バイエルのインスタグラム(bayerofficial) - 1月5日 23時28分

Producing Acarbose to Treat Diabetes
Diabetes is actually a condition that, depending on which stage it is at, responds well to treatment. As a result, the demand for antidiabetic medications is increasing in China. One Bayer antidiabetic product with the active ingredient acarbose is manufactured in Wuppertal, the site where Bayer was founded. Approximately 80 percent of the produced substance is exported to China. “Acarbose is produced biotechnologically by the Actinoplanes bacterium,” explains Till Zemke, plant manager for acarbose active ingredient production at Bayer in Wuppertal. In view of the huge demand, ­Bayer researchers have been working steadily for more than 20 years to improve the manufacturing conditions for acarbose. In recent years, cutting-edge technologies have made it possible for researchers to scrutinize the strains of Actinoplanes bacteria that are used in the production of acarbose in great detail.
More than 3,000 tons of acarbose have been produced at Bayer’s Wuppertal site and exported to various parts of the world since the product was launched.
Worldwide, some 415 million are affected by diabetes today – by 2040, that figure could be 642 million.
Type 2 diabetes is on the increase all over the world, especially in Asia where more and more people are now affected. The medical need for acarbose, an active ingredient produced by bacteria, is increasing.
New molecular biology methods can be used to selectively optimize the bacteria strains that produce the active substance. Using optimized microbes can help to make acarbose production even more efficient.
Learn more in Bayer’s “research”-Magazine.
Find the link in the bio.
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